The National Anti-Doping Agency of the Republic of Uzbekistan was established on the basis of the decision of the President of the Republic of Uzbekistan No. PQ-3457 of January 3, 2018 "On measures to organize the activities of the National Anti-Doping Agency of the Republic of Uzbekistan".

According to this decision, the Agency will conduct its activities in the field of prevention of doping in sports and effective implementation of the unified state policy in the field of combating doping, the International Convention on Combating Doping in Sports, the World Anti-Doping Code and other international anti-doping standards. in order to ensure compliance with the requirements, as well as taking into account the recommendations and suggestions of the World Anti-Doping Agency.

The agency operates on the basis of the Regulation of the Cabinet of Ministers of the Republic of Uzbekistan dated February 23, 2018 "On the National Anti-Doping Agency under the Cabinet of Ministers of the Republic of Uzbekistan". This Regulation defines the agency's status, main tasks, functions, rights, responsibilities, organization and reporting procedure, as well as the functional tasks and responsibilities of the head of the Agency.

On April 6, 2021, based on the decision of the President of the Republic of Uzbekistan No. PQ-5057 "On measures to further improve the activities of the National Anti-Doping Agency of the Republic of Uzbekistan", the Agency's activities were brought to a new stage and the material and technical base was strengthened.

Decision of the President of the Republic of Uzbekistan No. PQ-149, adopted on May 8, 2023, "On measures to effectively organize the activities of the National Anti-Doping Agency of the Republic of Uzbekistan within the framework of administrative reforms", introduces fundamental changes in the activities of the Agency. started. Based on this decision, the National Anti-Doping Agency was reorganized into the National Anti-Doping Agency of the Republic of Uzbekistan, and the "Road Map" on the transformation of the agency's priorities, organizational structure, and activities was approved.

According to this decision, the following are the priorities of the National Anti-Doping Agency:

a) implementation of a unified state policy in the field of prevention of doping in sports and fight against doping;
b) on the basis of the World Anti-Doping Code and international anti-doping standards, to develop drafts of national anti-doping rules and normative legal documents regulating the field and make proposals for their improvement;
v) regularly taking and checking doping tests from athletes in Olympic and non-Olympic sports;
g) controlling the use of drugs and other substances with a pharmacological effect in sports using an effective system of anti-doping control;
d) use of the online system for anti-doping administration and management (ADAMS system) designed to organize doping tests and other elements of doping control, collect and store information about athletes of the country;
e) expansion and strengthening of international cooperation with leading foreign organizations for mutual exchange of advanced methods and technologies in the field of anti-doping control and their introduction;
j) to help improve the qualifications of medical staff of sports federations, clubs and teams, to provide them with methodological assistance in the prevention of doping in sports and the implementation of anti-doping control, to implement educational programs, to promote healthy and honest sports to make;
z) coordination of mutual cooperation of physical training and sports organizations, state bodies and other organizations in the field of anti-doping control.